Stevens Johnson Syndrome: when drugs make your skin fall off

1551 points - 1 years ago - 700 Visit on Reddit - WTF?!

  • luxuri

    1 years ago

    learned about this in clinical today. Apparently if they don't die from it, the skin eventually heals completely and looks as new and soft as a baby's skin! They're treated similar to burn victims and if they manage keep infection away they'll have almost no scarring afterwards.

  • DikembeMutumBro

    1 years ago

    As someone who has had Steven Johnson Syndrome and recovered from it (On Two Different Occasions) This pic is one of the most rare and fucked up cases Ive ever seen. It never gets that bad. When I had it (I had mono and a doctor prescribed me Doxycycline an antiobiotic that HEAVILY reacts with Mono-antibodies) My case was similar to really bad chicken Pox everywhere (YES even my dick). My case was so severe that the Nurse said "Ew Do I really Have to Touch You?" When i was in the Emergency Room. However I looked nothing like the picture.

    Tl;DR As a recovering Extreme Steven Johnsons Syndrome patient, this case is one in a million. But that shit aint nothin to fuck with.

  • DeLaNope

    1 years ago

    I cared for one woman who got Toxic Epidermal Necrolysis Syndrome (TENS) from acetaminophen, (Tylenol..... She just had a headache, fuck her, right?). TENS is rather like Stephen Johnson's Syndrom's vicious brother.

    Anyway, her skin was sloughing off all over. I was told to assist with the (extensive) dressing change. Halfway through, I lifted the woman's forarm, meaning to raise it so the other nurse could wrap it. NOPE. The skin ripped at the elbow- and her arm literally dropped out of her skin. I was left holding an inside out glove of skin attached only at the fingertips. The arm kind of dangled there like a skint rabbit for a few seconds as the nurse and I stared at each other in horror.... And then we both turned to the woman's daughter who had been standing in the far corner watching us. Oops.

  • cyclefreaksix

    1 years ago

    I've taken care of two patients with this in 15 plus years of nursing. And, it's not just anesthesia that causes it.

  • wortelcake

    1 years ago

    I DO NOT WANT TO KNOW WHAT HAPPENED TO STEVENS' JOHNSON!

  • mr_e_us_lurker

    1 years ago

    My wife (gf at the time) had this almost ten years ago. It can happen with drug combinations (anti-depressants, steroids, otc stuff), and it almost seems like a set of reactive symptoms more than a concrete disorder. At least, that's the idea I got from hearing any doctor talk about it at length (it's still largely a mystery, and you'll never hear a doctor just say "I don't know).

    Anywho, my wife's skin acted like it had a 1st degree burn over her entire body. She was diagnosed/treated in time, so thankfully no permanent damage. She *did have a flake of skin the size of a dinner plate come of her stomach (sorry no pics). That was gross.

  • Supersofies

    1 years ago

    I acctually had this last year, though not as bad as this photo. I can post some pictures if wanted?

  • designofeye

    1 years ago

    My sister almost died from this from taking Lamictal, a drug I was also on. She was in an induced coma for over a month at a burn center. Her skin blackened and fell off. She was swollen everywhere (her lips were terrible and kept cracking open and bleeding) and twice her size.The worst was her eyelids had to be scraped to keep them from growing to her eyeball.She still has residual puffiness, and lost part of her long term memory as well as a trach scar on her throat.

  • kungfoojesus

    1 years ago

    Seems more like toxic epidermal necrolysis, but I've never seen either case.

  • BYoungNY

    1 years ago

    Teamocil. Not even once.

  • Coffee_Ink

    1 years ago

    I had this five years ago and it was this bad (or close). I was in a coma in a burn unit for tens days, blinds for months, lost my nails and part of my hair, and had a hard time breathing. If you looked at me today, you'd never know I had it. I actually completed an Ironman two years ago. The thing that really sucks is that I don't know what caused it, so I live in fear that I could have another reaction any day. It sucks, but it could be so much worse.

  • TheCathal

    1 years ago

    I should really REALLY learn not to click things like this.

  • nobodys_darlings

    1 years ago

    Didn't a little kid get this from Bayer recently? He was awarded 60 or so million dollars

  • TenSecondsFlat

    1 years ago

    "What's the matter smoothskin? Never seen a ghoul before?"

  • XisanXbeforeitsakiss

    1 years ago

    Im guessing the 'gunk' theyve put on his skin is to protect what remains of it. what is the gunk?

  • somverso

    1 years ago

    PRAISE NURGLE

  • chunklemcdunkle

    1 years ago

    Oh wow. Had a small case of this. This picture is a little extreme, though. This guy had a really really bad reaction.

    I had a series of terrible dental visits filled with malpractice and incompetency which left me with a nasty infection. They put me on an antibiotic called Clindamycin and I had came down with SJS.

    What was crazy is that my fingertips and the soles of my feet were extremely painful, to the point of needing thicker, softer socks just to get up.

    Another thing; at the time I played a whole lot of guitar and my calluses at the time had become harder than usual. When I say harder than usual, I mean I could tap on things louder with my fingertips than I could with other objects like pens.

    About a week or two after we figured it out and took me off of this stuff, I stopped hurting, and then the peeling happened.

    For some reason just my fingertips peeled, not my feet. Possibly the calluses were just shedding off, but man it sucked. I peeled off the calluses bit by bit for a few days, and in the end I had a fresh new layer of skin. Almost too fresh. It was tender, brand new, and reminded me of a crab that just moulted.

  • gaelicghetto

    1 years ago

    Ironic, I was just describing this syndrome to a friend the other day. I'm a speech-language pathologist and on my very first weekend as a therapist I was covering at a women's hospital in Pittsburgh. I got called to the ER for a woman suffering from it; she weighed ~450 lbs, was naked and splayed out on some weird fabric...splayed out as in her arms and legs were being held midair, full display. I was called in to see whether she was safe to swallow and re-initiate a diet. Typically this syndrome causes severe ulcers that cover the linings of the oral, pharyngeal, and nasal cavities. When she opened her mouth for me, I thought an Alien was breaking free from its egg. Nevertheless, she was able to swallow so no feeding tube, but man I'll never forget it...that and the next week I was helping run a nasoendoscopy on a man with gangrene on his genitals.

  • edubinthehills

    1 years ago

    Typically id like to say something funny, but this is just unfortunate.

  • MidnightDanger

    1 years ago

    Not even once.

  • slimzimm

    1 years ago

    It looks worse than it really is due to the gunk they put on him. Also, is that ETT just clear taped?

  • jakadamath

    1 years ago

    My grandpa had Steven Johnson Syndrome. That is all.

  • someGuyYouDontkown

    1 years ago

    Lamictal is known to cause this among other prescription drugs. Street drugs don't cause this. My cousin had this a couple months ago.

  • the_next_star

    1 years ago

    Goddamit, I opened this not knowing what I'd get, and I definitely didnt prepare myself fully when i didnt see an NSFW tag

  • chowingmein

    1 years ago

    I didn't even bat an eyelid, what the hell is wrong with me.

  • MrChunkyFunk

    1 years ago

    Anybody listen to Ab-Soul? He mentions dealing with this in Book of Soul, it's why he's a self-proclaimed "Black-lip-bastard" haha

  • adypants

    1 years ago

    It's like a fun chemical peel.

  • Rawsheeve

    1 years ago

    shoulda had a v8

  • EwokWrangler

    1 years ago

    Oh my goodness. How unlucky. Is he okay now?!

  • litsax

    1 years ago

    I actually had this syndrome when I was in second grade. I got it after running a high fever and taking ibuprofen (active in motrin and advil). From it I developed pneumonia and ended up incorrectly diagnosed as chicken pox until it would't go away and started to get worse. I was out of school for a month and would have been longer had I not first reacted over Christmas. Thank god I didn't have an extreme case but the month and a half I had it was pretty much hell. Anybody curious?

  • Irishbagpipes

    1 years ago

    My dad got this last April. Got it from gout medicine. They identified and treated it before the skin started falling off though.

  • hinckley

    1 years ago

    But hey, on the bright side: free straw!

  • Mister_Smith

    1 years ago

    i had a nasty infection a few years ago and the doctor thought i had this. needless to say, i was scared.

  • kill_all_hippies666

    1 years ago

    I'm on meds that can cause this disease. Happy I did'nt get it!

  • troyyya

    1 years ago

    Reading the comments here makes me never want to take medicine again.

  • Chingpong123

    1 years ago

    I regret clicking that link.

  • Scarfie91

    1 years ago

    Sulfonamides are one of the main ones that cause this. Nasty shit.

  • ClowninOnYa

    1 years ago

    Awwww she/he is blowing bubbles!!

  • GoToCollegeTheySaid

    1 years ago

    That's a funny name for a horrible disease.

  • dwightmoody

    1 years ago

    Happened to a friend of mine. He's fine now.

  • schibbyzolta

    1 years ago

    How does someone get SJS? Like is it hereditary or transmitted or how? Sorry for being lazy and not looking it up but I assume others are curious as well.

  • monkeyfeets

    1 years ago

    Ahhhh my coworker has this and is recovering. She looks like she has really bad chicken pox.

  • Brendancs0

    1 years ago

    is this from allergic reaction

  • Zetzu1

    1 years ago

    One of my best friends had this. His skin didn't fall off but he had huge ulsurs all over his body, including his internal organs and his throat. It's been about a year and he still has new skin spots all over his body

  • Lord_Giraffe

    1 years ago

    That looks unpleasant.

  • Christianous

    1 years ago

    I actually had this. It was a bit of a minor case, it was mostly in my mouth and eyes. Worst month of my life.

  • Malandris

    1 years ago

    A little girl in Plymouth had this happen to her a decade ago from children's Motrin.

    Lawsuit

  • Luxpreliator

    1 years ago

    The phrase kill me now seems appropriate.

  • elitechad255

    1 years ago

    I remember them talking about this on an episode of ripleys believe it or not. The ladies skin was as thin a rice paper just after it began healing again.

  • cheerkitten69

    1 years ago

    Omg could imagine being the person this is named after?!

  • delijah60

    1 years ago

    "Its whats on the inside thats beatiful. " really cuz that inside is pretty fucked up

  • Wistuba17

    1 years ago

    My mum has this syndrome, however she has had nothing even close to this, maybe a few blisters but this shocked me.

  • Music_Saves

    1 years ago

    Viagra, side affects: if ur face begins to fall off see a doctor immediately. Splash with vinegar to fight infection. Luckily ur face will be baby soft afterward (I know this because I read it on reddit)

  • essentially

    1 years ago

    Pro tip: the drug cyclosporine will stop this reaction dead in it's tracks if taken in the first few days. For some reason this treatment remains largely unknown.

  • babyunagi

    1 years ago

    Okay, I'll say it...I've never had this.

  • halo268

    1 years ago

    Well thanks for sharing this gem

  • c_hawkthorne

    1 years ago

    /r/palatecleanser

  • I_didnt_even_know

    1 years ago

    his(?) face looks like a wad of chewed gum

  • JoseNotHose

    1 years ago

    It's a bad idea to have WTF and porn both on the front page and accidentally click WTF while its happy time.

  • Revslowmo

    1 years ago

    Looks like a cuff leak on the ET tube, you shouldn't have bubbles coming out of the mouth.

  • Cic3ro

    1 years ago

    Tobacco is wacko!

  • TheJasminDragon

    1 years ago

    My mom had this when she had cancer, It deformed her face and she became blind and handicapped. This shit isn't something to fuck with, I've seen it first hand.

  • killmesara

    1 years ago

    I know a gal who got this because of an allergic reaction to antibiotics.

  • automagnus

    1 years ago

    It's a known side effect of sulfa based antibiotics and I was warned about it when I took one (Sulfamethoxazole/Trimethoprim), however I would have died without the antibiotic, so it was well worth the risk.

  • TresDelConwayJuan

    1 years ago

    So don't kill it?

  • atticusmas

    1 years ago

    One day, you will see an awful WTF picture that makes you un subscribe.

    This day has come.

  • santh91

    1 years ago

    Code name "Reptile"

  • babdady

    1 years ago

    Just Wiki "stevens Johnson Syndrome" it can be caused by infections. It usually follows common infections such as herpes simplex virus, influenza, mumps, cat-scratch fever, histoplasmosis, Epstein-Barr virus, mycoplasma pneumoniae, or similar. Stevens–Johnson syndrome (SJS) is thought to arise from a disorder of the immune system.[3] The immune reaction can be triggered by infections, drugs, or medications.[citation needed] In some groups, drug reaction may be aggravated by genetic factors.[

  • regalhornet

    1 years ago

    My mom had this but it never got this bad and I'm thankful she's still alive. It also makes all of your orifices blister up. She had blisters on her eyes, in her throat, and even inside of her vagina/urethra.

  • jamz666

    1 years ago

    mind telling me what kind of drugs? id like to avoid this if at all possible.

  • jessbird

    1 years ago

    TIL never take any drugs ever again

  • about26ducks

    1 years ago

    I know for a fact, that it is not Lupus...

  • DSEthno23

    1 years ago

    Now THIS is WTF! Not dozens of the same throat slitting pictures!

    But what drug caused this??

  • Shit_The_Fuck_Yeah

    1 years ago

    I'm sorry, what kind of drugs do this?

  • r_house

    1 years ago

    and I'm not going to sleep tonight. Thanks accidental WTF click.

  • darkkefka

    1 years ago

    No Fallout jokes? I'm surprised reddit.

  • liftliftliftliftlift

    1 years ago

    how do i know if i got it?

  • JimRazes00

    1 years ago

    I don't want to see this! Put a fricken nsfw tag

  • CoffeeOwls

    1 years ago

    Nursing student here. Had a kid who got a rash after taking an anti-seizure drug post-concussion. He was febrile and itchy, the doc said he just had a virus. Nope, Stevens-Johnson syndrome. Pretty miserable for a week until his mom took him into the ER and they figured it out.

  • NinjaBullets

    1 years ago

    wonder why the hair hasn't fallen off

  • Batani

    1 years ago

    Should I feel bad that a disease has the same name as me?